![]() ![]() 8 This fever usually lasts 1 to 2 weeks but may last up to 5 weeks. The pharyngitis could be exudative or nonexudative, may have petechiae on the soft palate, and may look like streptococcus pharyngitis.8 The fever typically ranges from a temperature of 100☏ to 102☏ but can get as high as 106☏. The physical symptoms of IM are similar to those of many other bacterial and viral infections. 7 Less common symptoms include palatal petechiae and periorbital edema. 6,7 Abdominal pain/nausea/vomiting occurs in about 17% to 18% of both adults and children, headaches occur in about 38% of adults, and a rash can be present in about 8% of adults and 17% of children. 7 Fatigue and malaise, which can persist for weeks and even months, 6 are also very common, occurring in about 47% of adults and about 24% of children. Typical IM symptoms in adolescents and adults are fever, lymphadenopathy, and pharyngitis. 7 However, clinical presentation of IM can be very similar to that of other bacterial and viral pharyngitis infections, posing a challenge in diagnosis of IM.ĮBV-associated IM is also known as glandular fever, kissing disease, mono, mononucleosis, and Pfeiffer syndrome. ![]() 7 It is estimated that 30% to 77% of adolescents and adults will develop symptoms of IM. 7 Adolescents and adults are more likely to show classic IM symptoms, 7 but not all who become infected will have symptoms. 7 In infants and young children, IM is typically asymptomatic or may have nonspecific symptoms. 6 The development of symptomatic IM correlates strongly with age. It is estimated that more than 95% of the world’s adult population has been infected with the virus, but only some patients will become symptomatic with initial infection. 5 The Epstein-Barr virus (EBV), which causes infectious mononucleosis (IM), is extremely prevalent. 4 Other viral causes are coronavirus, coxsackievirus, cytomegalovirus, Epstein-Barr, herpes simplex, HIV, influenza, and parainfluenza. 2 Most often sore throats are caused by viral infections, 3 and 40% of these are caused specifically by adenovirus and rhinovirus. Sore throat is one of the top 10 complaints in primary care 1 and retail health. ![]()
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